Dimethyl fumarate and progressive multifocal leucoencephalopathy (PML) Introduction
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چکیده
Introduction Dimethyl fumarate Psorinovo® is not registered through the Medicines Evaluation Board (MEB). It is a compounded drug made by GMP compounding pharmacy Mierlo Hout in the Netherlands, and used for the indication psoriasis [1]. Psorinovo® has been compounded by pharmacy Mierlo Hout for 28 years. According to Dutch law Mierlo Hout pharmacy is regarded as a supplying-pharmacy. Dimethyl fumarate, registered as Tecfidera, was granted marketing authorization in the Netherlands on 30 January 2014 and is indicated for the treatment of adult patients with relapsing remitting multiple sclerosis [2].
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